GLP is a quality system to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of experimental studies. NILU’s Health Effects Group has implemented GLP as standard quality system to perform, develop and validate methods for in vitro toxicity testing of compounds such as chemicals, aerosols and nanomaterials.
GLP is a quality system to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of experimental studies. NILU’s Health Effects Group has implemented GLP as standard quality system to perform, develop and validate methods for in vitro toxicity testing of compounds such as chemicals, aerosols and nanomaterials.
Testing strategies on trial
The latter compound needs special attention: “So far, testing of nanomaterials has no specific regulations,” explains senior scientist Maria Dusinska, director of the Health Effects Laboratories (HEL) at NILU. “They are tested according to the guidelines for toxicity testing of standard chemicals. But nanomaterials have completely different properties and behaviour compared to traditional substances. This requires special routines and protocols for giving reliable results, as well as for the workers’ safety, in which the HEL group has already several years of experience.
Norwegian pioneer
In Norway there is no other GLP laboratory performing in vitro methods on human toxicity, so we have been working hard during the last months on developing and implementing Standard Operating Procedures (SOPs) that fulfill the requirements of GLP.” With success: the HEL group has received the confirmation that their laboratories are certified for GLP.
